Archive for the ‘Shoulder’ Category

Is your Abnormal Shoulder MRI Really Normal?

Tuesday, November 1st, 2011
shoulder mri surgery

Will your shoulder MRI lead to unnecessary surgery?

I’ve blogged before on a very scary trend that continues despite the evidence-many things seen on MRI and blamed for the cause of the patient’s pain that lead to invasive surgery are really normal findings. This has shown to be the case with knee MRIs. For years we doctors have chased around phantom meniscus tears while modern studies have shown that an awful lot of patients without symptoms have meniscus tears on their MRI. A recent NY Times piece highlighted a study by an orthopedic surgeon that showed the same thing for shoulder MRI. The study involved scanning the shoulders of 31 perfectly healthy baseball players without pain. Despite imaging normal players, the shoulder MRIs found abnormal cartilage in 90 percent and abnormal rotator cuff tendons in a whopping 87%! I love the quote from the surgeon, “If you want an excuse to operate on a pitcher’s throwing shoulder, just get an M.R.I.” The patient example mentioned in the NY Times story is typical of our experience. This patient went skiing and developed knee pain. An MRI seemed to show a tear in his ACL so two surgeons wanted to yank it out and replace the ligament. The third surgeon told him his ACL was normal on exam and found an occult fracture that was the real cause of his pain. The story highlights a huge problem. Many physicians have abrogated their exam to the MRI scanner and don’t practice the common sense combination of looking at the picture, listening to the patient, and performing a thorough exam. The upshot? We have many patients who come to us transfixed on their MRI as if it were the Oracle from Delphi and many have been told that they need invasive surgeries simply based on the MRI with little exam or history to corroborate what’s on the films. This includes patients who are about to have their entire knee, hip, or shoulder joint replaced but who actually have pain coming from somewhere else. If you’ve had a 5 minute evaluation where much of the time was spent transfixed on the MRI and very little was spent asking about the who, what, when, and where and on a good old fashioned exam, you may need a second opinion!

-Most Tears in the Rotator Cuff don’t cause Symptoms

-How Accurate is an MRI for Diagnosing Hip FAI?

-Finally a Way to Tell if that Meniscus Tear on MRI is Really causing Pain

-MRI of the Knee in Soccer Players-Interpret with Caution!

-Shoulder X-ray Findings not Related to Pain-No Surprises Here


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Can Stem Cells heal a Retracted Rotator Cuff Tear?

Thursday, July 21st, 2011

Retracted Rotator Cuff Tear Stem Cell Injection

While we have treated many partial rotator cuff tears with stem cells, we haven’t traditionally treated complete, retracted rotator cuff tears with stem cell injections. This was  due to our concerns that the two ends of the tendon or muscle would need to be surgically pulled together before stem cells might effect some healing. A ‘retracted” tear of the rotator cuff muscle or tendon is when the two sides of the tear pull back like a rubber band. They are literally ”bunched up” on either side of the tear. As a result of our concerns, we’ve always limited ourselves to treating rotator cuff tears where the two ends of the tear are close together or there are only small tears that need to be filled. All of that may have changed with patient JS, a very active 54 year old who injured his shoulder rotator cuff while lifting weights. JS had a 1.5 cm retracted tear (not huge, but sizeable) and was adamant about trying stem cell injections. We finally reluctantly agreed due to the fact that the patient was otherwise a perfect candidate (over the top fit and otherwise healthy). However, we used more specialized splinting of the shoulder, in contrast to the no splinting approach we would normally use with a nonretracted tear. The new bracing strategy was designed to overcome the retraction and bring the two ends of the tear closer together. He was then treated with a Regenexx-SD procedure with follow-up Regenexx-SCP procedures, using exact ultrasound guidance to ensure placement of the stem cells into he tear. The result? Much to our surprise, he reported 99% improvement over the three months and a follow-up ultrasound yesterday demonstrated excellent healing with some fill-in of the retracted gap. In particular, the image above shows that the “bunched-up” appearance of the retracted muscle portion has now changed to the appearance of a more normal rotator cuff muscle. In addition, the tear near where the tendon attaches to the bone has also filled-in. The upshot? We will track this patient further and get additional follow-up MRI imaging, but so far it does appear that a Regenexx-SD procedure with specialized bracing may be capable of filling in retracted rotator cuff tears. This may be an exciting development, allowing some patients who we thought could only be treated surgically to have a non-surgical treatment option.

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Rotator Cuff Surgery Rehab: Faster is Better

Saturday, May 7th, 2011

Shoulder stem cell

Extensive rehabilitation is often needed after a rotator cuff repair surgery because of the weeks of immobilization needed to help the sewn rotator cuff muscle or tendon to heal. This time in a shoulder brace (immobilized) can cause the muscles of the rotator cuff to become weak and in need of strengthening. The question is, should this rehab be performed slowly or can it be more aggressive? A study out this week suggests that more aggressive is better. The study looked at a slow rotator cuff surgery rehab protocol versus an accelerated rehab. The winner? The more aggressive rehab group had no more pain after surgery and much better function at 8, 12, and 16 weeks after surgery. The reason? We’re built to heal on the fly. Speak to any veterinarian who operates on animals and the concept of placing an animal in a brace and keeping them off the area for extended periods of time just won’t work. If you’ve ever watched a dog recover from surgery, they’re down hard for a little while and then the moment they can get back on the area, they hit the ground running. This is consistent with research models of healing-generally the more the part is used, the better it heals. Our experience with our stem cell shoulder rotator cuff treatment is the same, since less trauma occurs in an injection, an extensive period of downtime isn’t needed when treating a partial rotator cuff tear. As a result, we agree with the findings of this rotator cuff surgery recovery study, more aggressive rehab is better. In fact, we would go one step further, if there’s a partial rotator cuff injury, consider non-surgical, stem cell injection based methods of repair, which will cause even less immobilization of the shoulder and in our clinical experience, quicker recovery.

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Why do Women have More Problems with Rotator Cuff Surgery?

Sunday, April 10th, 2011

Shoulder rotator cuff healing stem cells

Interesting study out this week on women and rotator cuff shoulder surgery. In this study, women were found to have more pain and disability after rotator cuff surgery than men. The question is, why? Rotator cuff healing ability or time would depend on a few different things. First, size of the rotator cuff tear and other factors such as prior surgery. In this study, these things weren’t significantly different between women and men. There are another set of factors that are very important for proper rotator cuff healing-the local healing environment. One of the big players in this healing of rotator cuff tears is of course what effects all healing in the body-adult stem cells (see our medical practice’s book, Orthopedics 2.0 for more discussion on stem cells and healing). With our culture experience from the Regenexx-C stem cell procedure, when we analyzed our data, we did see differences in the stem cells of women and men (see graph above-the higher the bar the better the stem cells grew). While these differences weren’t significantly different for normal weight men and women (blue and red bars above-there is a difference, but this is not statistically significant), they became much more pronounced with heavier women (green bar above). What’s interesting is that normal weight men and heavier men didn’t have this same type of steep drop off in stem cell activity (blue vs. yellow bars above). The good news for heavier women is that in our procedure, this less robust stem cell growth didn’t seem to translate into a poorer treatment outcome. This may be because the Regenexx-C procedure can get so many more stem cells to the area when compared to the numbers involved in normal healing-essentially overwhelming the area. Why would heavy women in particular have adult stem cells that don’t grow as well? One significant reason may be hyper-insulinism and metabolic syndrome, which clearly has negative impacts at a cellular level. For example, we know that in rotator cuff repair surgery, bone and tendon healing is impaired if the patient is diabetic. We also know that patients with metabolic syndrome are “diabetics in training”, meaning that even though their blood work doesn’t yet define them yet as a diabetic, they’re in the early stages of the disease progression. If you have plans for rotator cuff surgery and are female, what can you do to increase your chances of healing? First, if you’re overweight, definitely consider going on a strict low glycemic diet before surgery (see #2-diet recommendations in the top 10 causes of cartilage loss list). A good way to follow your progress here would be to have your doctor measure and monitor your HBA1c, a measure of long-term blood sugar control. Second, in our opinion, many rotator cuff tears can be treated through injection without the need for surgery. Using this method, we see less significant differences in outcome between men and women through injection, even though there does seem to be a difference in stem cell activity.

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Most Tears in the Rotator Cuff don’t cause Symptoms

Sunday, April 3rd, 2011

shoulder mri rotator cuff tear

The ascendancy of MRI imaging as the ”gold standard” to find structural abnormalities in the body has been meteoric. In less than a generation, the medical world of diagnosis has been immeasurably enhanced by early detection of all sorts of problems from tumors to torn ligaments using advanced imaging. However, this explosion in our ability to find abnormalities in structure has come at a price in the areas of orthopedics and pain management. It all began when researchers wondered if everything we see on these scans is actually causing symptoms. This steady stream of published research has marked what I am now beginning to call, the slow and steady end of the structural model of pain. Let me explain. It used to be commonly thought that every small Ditzel seen on an MRI meant something was wrong and in need of some surgical treatment. This approach has led to millions of surgeries worldwide for the treatment of pain. This way of treating pain would only make sense if we had good research showing that everybody without pain had a normal MRI and everyone with pain had an abnormality on their MRI. However, many different things in the body can cause pain in a given area like the shoulder or the knee. So if for example research revealed that a lot of patients with normal scans have pain and  many patients without pain had abnormal MRI’s, then physicians would have to take any MRI abnormality with a “grain of salt”. In medical terms, this is known as a false positive (the test for the disease shows positive but the patient really has nothing wrong with them). Let me give an example of a patient with shoulder pain. The following is a short list of things that can cause shoulder pain: rotator cuff tears or shoulder arthritis, a pinched nerve in the neck, or damaged/arthritic joints in the neck. In our patient, if rotator cuff tears are common in patients who don’t report shoulder pain, then finding a rotator cuff tear on MRI doesn’t get us any closer to determining if that rotator cuff tear is causing the patient’s shoulder pain. For all we know it may just as easily be a pinched nerve in the neck or a damaged neck joint. This problem of a false positive with MRI already exists in knee patients with knee meniscus tears-large studies have concluded that knee meniscus tears are common in middle aged and older patients without knee pain. Regrettably for doctors, things just got more complicated when it comes to a diagnosis of what causing shoulder pain based solely on an MRI. A large Japanese study published this week demonstrated that 2/3′rds of patients without shoulder pain had rotator cuff tears. The authors did make some suggestions for trying to correlate MRI rotator cuff tears findings using physical exam in patients with shoulder pain; such as making sure the patient had a positive impingement sign and weakness in external rotation. These recommendations bring up a critical point, that an MRI without a good physical exam is often meaningless for determining why someone is hurting. Too often these days we physicians substitute an MRI report for actually placing hands on the patient and getting a good history and regrettably this often leads to unnecessary surgery. The upshot? It’s imperative that whatever MRI findings you have (whether the abnormality is in your shoulder, knee, or another joint) be confirmed on examination as the likely cause of your pain. If patients don’t insist on this important step, then shoulder surgery for a normal MRI finding related to normal aging may be in their future! If there’s any question of whether the pain is really coming from the joint, request that the doctor numb up the area under imaging guidance (called a diagnostic block) to ensure what’s being seen on the image is really causing pain.

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Do we know Shoulder Replacement Works?

Monday, March 21st, 2011

Shoulder replacement surgery alternative

Shoulder replacement is a tough surgery sometimes recommended when the shoulder is chronically painful due to severe arthritis. I remember back in residency learning that patients with shoulder replacement had a much more protracted recovery and were often left with continued pain despite the invasive surgery. The reason given then is still the same, the shoulder is a complex joint with many directions of movement, so unlike replacing a hip with a deep ball and socket joint, replacing a shoulder is different. The shoulder socket is shallow, so keeping the ball of the shoulder in it’s socket is largely accomplished by muscles. The trauma from the invasive surgical implant of the new joint and the long-term recovery time from shoulder replacement surgery often causes these stabilizing muscles to atrophy, leaving the remaining joint weak. You might think that with all of the big resources poured into shoulder replacement joints we would have good research showing that replacing the shoulder is better than not replacing the shoulder. However, no such data exists according to a recent study looking at research in this area. This review of many published studies concluded that we really didn’t know if shoulder replacement was better than leaving the shoulder alone and recommended more research. More recently, “resurfacing” or a “Birmingham” shoulder replacement has been all the rage, but these minimal shoulder replacements have problems related to their metal content. These smaller prostheses such as the metal on metal (MOM) type have well documented safety issues. In fact, these MOM joints were the target of several negative studies at the recent AAOS meeting where researchers demonstrated severe adverse health effects in some patients from wear particles released by the metal. If replacing the joint isn’t a good option, what else might work to help treat the pain of shoulder osteoarthritis? A small pilot study shows that two injections of hyaluronic acid (aka HA or artificial lubricants like SynVisc, OrthoVisc, Supartz, Hyalgan, etc…) helped most patients get by with less pain and increased function. Injecting steroid medications into peripheral joints like the shoulder can help short-term, but these injections don’t offer as much prolonged relief as HA injections. This longer term effect of HA injections was also echoed by a larger study that compared HA to steroids for hand arthritis. There are also other reasons to be wary of steroid injections in joints, as the combination of anesthetic and steroid commonly used by many physicians can kill off remaining cartilage cells. We’ve also seen good results with the injection of the patient’s own stem cells to treat shoulder arthritis. This procedure may be regenerative in that it may help the cartilage in the joint. The upshot? Until we have better data, you may want to stay away from invasive shoulder replacement surgery and consider looking at non-surgical options like hyaluronic acid injections or cell based therapy.

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AAOS PRP Studies: Huh?

Saturday, February 19th, 2011

The evolution of a new medical technique follows a predictable sequence of events. First, a few brave pioneers try something new and see dramatic results, then business gets involved to create hype, the hype peaks just as the new technique gains wide popularity and everyone believes the new technique is better than sliced bread. The final act of the play is a bit like a Groucho Marx saying, “I would not join any club that would have me as a member…” Meaning, by the time the technique reaches wide acceptance, the careful controls used by the original brave few to get great results have disappeared and studies invariably show that the technique used differently in the hands of others doesn’t work that well. Such is the predictable rise and fall of PRP at the AAOS meeting this week. Three surgical studies not using PRP (Platelet Rich Plasma), but PRFM (a PRP cousin that traps platelets in a dense clot), showed that surgeries with a PRFM clot implant were no better than shoulder surgeries without the clot. The first thing that comes to mind is, wasn’t PRP supposed to prevent the need for shoulder surgeries since most shoulder surgeries have not been shown to be more effective than no surgery? The fourth study is equally confusing as a surgeon performed PRP injections into 5 NFL players with acute hamstrings injuries and 5 other players underwent traditional rehabilitation. First, it’s amazing this study made it to the podium, as any study with 5 subjects in each group is only an early pilot study and there was nothing else compelling (like changes in imaging) to make the study interesting. The author concluded that since there wasn’t a difference in time till return to play between the two groups, the PRP didn’t work. The biggest issue with this study is that these were fresh injuries (17-20 days old). In our clinical experience, PRP works best to help something heal that’s having difficulty healing on it’s own. A highly active athlete with a week old hamstring injury is not in this category, in fact his hamstring is still healing on it’s own. So why would we expect PRP to hasten the recovery of an injury that’s expected to heal on it’s own? In addition, while the number of subjects are really too small to analyze, the longest it took to heal a player in the PRP group was 30 days compared to 81 days in the rehab group. Also the range of healing times in the rehab group (8-81 days) shows that there were at least two types of hamstring tears present in these players-the very mild type that would get better quickly on it’s own and the very severe type (perhaps spinal nerve root problems that went undetected? see our practice’s Orthopedics 2.0 book). As a result, there’s no way to tell if the PRP or rehab groups had more or less of these severe hamstring injuries, which would skew the small dataset severely. Finally, while the press releases don’t say, I have to assume that these were blind injections of PRP, so there’s no way to tell if the injections were actually in the hamstrings tendon (see our posts on accurately placing cells versus blind injections).

So what’s the real problem? One of the surgeon authors quoted made a really smart observation in saying that no study at AAOS had characterized these cells to know what was actually being injected. As I have blogged before, producing PRP in a bedside centrifuge is easy, but you have no idea what you’re getting out. Is the PRP concentrated enough? Too concentrated? Does the patient have enough of the right kind of growth factors in his or her cells to get the job done? As my Groucho Marx sequence of medical procedure adoption predicted, putting new tools in the hands of the masses who eventually use them differently and then study these new uses, is an important part of the adoption of new health care technologies. However, it is painful to watch!

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If you Ignore a Rotator Cuff Tear: Will its Size Change?

Wednesday, February 16th, 2011

shoulder rotator cuff tear surgery alternative

Shoulder rotator cuff tears are common problems of aging, usually caused by less blood supply in the aging rotator cuff and changes in the surrounding tissues that then place pressure on the muscle or tendon. For small tears, the conventional wisdom has been to leave the tear alone and to pursue conservative treatment such as physical therapy, medications, and home exercises. For larger tears, surgery is usually recommended as soon as they’re found. However, a new study suggests that you may want to monitor the tear for awhile before you take some action, as about half will increase in size if left alone and half will stay the same size. The researchers took 51 patients with 61 rotator cuff tears and measured these on MSK ultrasound (orthopedic type ultrasound performed by a skilled doctor in the office). They then went back and looked at the tear size at a mean follow-up of almost 3 years later. At that point, most of the tears (49%) had increased in size, about the same number hadn’t changed (43%), while the minority (8%) had gotten smaller. The tears that did get bigger weren’t found more often in older patients as one might expect and the bigger tears weren’t the ones that got bigger three years later. The single biggest predictive factor for a tear that was getting bigger was that the patient reported significant pain at the time it was first measured. Since the authors measured the size of the tears using ultrasound, this test can be inexpensively accomplished in a doctor’s office (assuming the doctor knows how to use ultrasound). So if you have a tear causing a lot of pain, it may make sense to find a physician skilled in MSK ultrasound to check the tear size once every few months to make sure it’s stable. If it is getting bigger and the tear is not retracted, then non-surgical injection therapy to heal the rotator cuff tear is your next step. If the tear is very large and the ends are retracted like a broken rubber band, then surgery may be indicated to repair the tear.

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New Study: Calcium Deposits in Shoulder Tendons can be Treated Effectively without Surgery

Saturday, February 12th, 2011

shoulder calcific tendonitis treatment avoid surgery

Calcific tendonitis means that your tendon has “dead” areas that have turned to bone. These calcium deposits in the tendon obviously make the tendon less compliant and more stiff. A tendon is the part of the muscle that attaches to bone and often acts like a rope going through a pulley or being pulled over a fixed point. Think about what would happen if you cemented portions of the normally supple rope so that they were stiff. As the rope was pulled through a pulley, it would more easily get stuck. This is what happens in calcific tendinitis. As a result, these areas of calcium deposits in the tendon can also cause irritation of the surrounding tissues which can cause pain and swelling. Traditionally, these areas have been cut out using open surgery, but this method is very invasive and has all the possible complications and side effects associated with a big shoulder surgery. A new study confirms what we’ve known for awhile, which is that a trained physician can get rid of these calcium deposits in the tendon with an ultrasound machine to guide a needle, rather than surgery. In this study, 34 shoulder tendons were treated and 6 other tendon areas. There was a reduction in the size of the calcium deposits on follow-up imaging and 80% of the patients had more than a 60% reduction in the size of their lesions. A very low complication rate was found and good clinical results. This technique is also known as “barotage” and can also be used to get rid of bone spurs through a needle. So for calcium deposits in your tendons, surgery doesn’t appear to be the best choice, instead using a needle to break-up and dissolve the area is likely a less invasive choice to help you avoid more invasive surgery.

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Getting Rid of Shoulder Trigger Points: An Effective Therapy to Help Avoid Shoulder Surgery?

Sunday, January 30th, 2011
avoid shoulder surgery alternative

avoid shoulder surgery alternative

Have you had this experience? You see your orthopedic surgeon who spends a few minutes performing an exam, looks at your films, and suggests shoulder surgery. But do you really need shoulder surgery? Are there much less invasive options? Is there a shoulder surgery alternative? While we often treat many smaller rotator cuff tears and other shoulder problems with stem cells, we also believe that some shoulders don’t even need that level of care. Many patients will get better by getting rid of myofascial trigger points with an IMS technique. Never heard of this therapy? You’re not alone. I explain trigger points and IMS it in more detail in our medical practice’s book, Orthopedics 2.0. Briefly, muscle trigger points are spots in the muscle that become painful and locked, so that the muscle is painful and weak. These spots can be simply cleared by a well trained provider with an acupuncture needle (however IMS isn’t Chinese acupuncture). Now a new study published by one our colleagues shows that IMS is effective in a randomized controlled trial. The results of the study showed that a three month program of IMS is more effective than no treatment. Based on experience, I would say that many of these patients with simple shoulder muscle trigger points often get unnecessary surgery. Why haven’t you heard of this very valuable treatment that is much less invasive than surgery? The economics of medicine. Trigger point injection therapy (either Travell type with the injection of anesthetic or IMS) don’t pay well, so these therapies have become a lost art. However, apparently a lost art that’s effective and based on the low invasiveness of the technique, in our opinion, far safer than surgery.

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