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Regenexx® Stem Cell & Platelet Procedures for
Foot & Ankle conditions.

Regenexx® Stem Cell & Platelet Rich Plasma Procedures are the world’s most advanced regenerative injection treatments for treating foot and ankle conditions. Before you consider ankle surgery, fusion or replacement, consider the world’s leading stem cell and prp injection treatments.

Current surgical treatment options for common injuries and arthritis, include ankle arthroscopy to “clean up” damaged cartilage, fusion of ankle bones where cartilage has been lost, and tendon grafts screwed in place to strengthen loose connections between bones. All are painful and may not be effective in the long run. These surgeries typically involve a painful post surgical recovery with a lengthy rehab period to restore strength and mobility to the ankle.

Patient Outcome Data & Commonly Ankle & Foot Conditions

Regenexx is the only stem cell treatment network to publish this type of analysis of patient stem cell procedure outcome data. The analysis is made possible thanks to the massive numbers that are compiled throughout the years in the Regenexx patient registry, which tracks patient outcomes at regular intervals following all of the stem cell procedures we offer.

Note: This patient outcome data is not part of a controlled trial. Every patient becomes part of a registry to track outcomes and any complications. This data is a compilation of patient input to the Regenexx Patient Registry at regular intervals following their Regenexx Procedure. In addition, none of this data may be reproduced in any way or displayed elsewhere without prior written permission from Regenerative Sciences.

  • Foot and Ankle Patient Outcome Data

    Most of the foot and ankle patients in this data summary had either moderate or severe main ankle joint arthritis, with many also having either lax ligaments and/or partial tendon tears. A few patients also had sub-talar arthritis. Because this is a smaller data set, all time points were collapsed, such that the last available report was used ( about 17 months post procedure on average).

    View Foot and Ankle Patient Outcome Data

Commonly Treated Ankle & Foot Conditions

This is not a complete list, so please contact us or complete the Regenexx Candidate Form if you have questions about whether you or your condition can be treated with these non-surgical procedures.

  • Arthritis
  • Ankle Instability
  • Peroneal tendon tear or split
  • Ligament sprain or tear
  • Sub-talar arthritis or instability
  • Tarsal tunnel syndrome
  • Plantar fasciitis
  • Bunions

How it Works

Stem Cell Treatments

Same Day Stem Cell Protocol (USA & International) & Cultured Stem Cell Procedure (Cayman Islands Only)

Adult stem cells are cells from your own body that can renew themselves and turn into other cells (differentiate). They live inside all of us in various tissues, poised to leap into action to repair damage as it occurs. As we age or have big injuries, we may not be able to recruit enough of these cells to the site to fully repair the area. Regenexx Stem Cell Procedures help overcome this problem by extracting stem cells from an area of high volume, then concentrating the cells and reinjecting them into the damaged area to help the body heal naturally.

Our Patented Stem Cell Procedures can be used for a wide range of conditions and are the tool of choice for injuries, arthritis and other conditions that may be more significant than what may be treated with our Platelet Rich Plasma or Platelet Lysate Procedures.

Blood Platelet Treatments

Super Concentrated Platelet Rich Plasma & Advanced Platelet Lysate Procedures (USA & International)

Platelet Rich Plasma (PRP) and Platelet Lysate Injection Treatments contain healing growth components from your own blood that increase your body’s natural ability to repair itself. The use of PRP to repair joint, tendon, ligament, and muscle injuries is becoming well known, thanks to exposure from professional athletes. Platelet injection treatments are effective because they have a stimulating effect on the stem cells within the targeted area, making those stem cells work harder to heal damaged tissues.

Our Advanced Platelet Procedures are more pure and concentrated than those created by the automated machines used at most regenerative medicine clinics. Platelet procedures are commonly used for soft tissue injuries, mild arthritis and spine conditions.

Regenexx Procedures at a Glance

Typical Condition Severity

$$$ Cultured Stem Cell Procedure (Cayman Islands Only)*
$$ Stem Cell Treatment Protocol (USA & Worldwide)
$ Platelet Rich Plasma & Platelet Lysate
Strains, muscle, ligament & tendon tears, overuse injuries, tendonitis & tendonosis, minor arthritis, joint maintenance, bulging or herniated discs, degenerative discs.
More severe muscle, ligament & tendon tears (including complete tears), joint arthritis, degenerative joint conditions, torn spinal discs, degenerative discs, avascular necrosis, bone conditions & non-union fractures.
Similar to USA Stem Cell Treatment, but stem cells are cultured to greater numbers.* Recommended for severe injuries, arthritis, advanced degenerative conditions, more severe spine conditions.
*Advanced culture expanded stem cell procedure-not approved by the USFDA and available only through licensed sites where culturing cells are the practice of medicine.

The Most Advanced Orthopedic Stem Cell Protocol in the World

  • 100% Focused on Orthopedic Conditions & Producing the Best Possible Outcomes
  • Up to 20 Times More Stem Cells Than Standard Stem Cell Procedures
  • The Most Researched Stem Cell Protocol for Orthopedic Conditions
  • Image-Guided Cell Injections & Harvesting for Absolute Precision
  • Bone Marrow Derived Stem Cells Outperform Fat Derived Cells
  • A Complete Stem Cell Protocol - Not a Single Procedure
  • Annually Published Patient Outcomes and Safety Data

Explore The Regenexx Difference

Ankle Ligament Tears, Sprains and Instability of the Ankle Joint

When the ligaments that hold the bones of the ankle joint together are partially torn or stretched, as in the case of a bad sprain or repeated minor sprains, they can become painful, loose, and weak. This changes how you walk, putting painful stress on other joints of the foot, as well as making it more likely that you will sprain the ankle again. This leads to a cycle of chronic pain and instability.

Ankle sprains and injuries that are not too severe, may be resolved with Regenexx super concentrated PRP (platelet rich plasma) procedures. These procedures are intended to help heal damaged tissues and tighten lax ligaments due to sprain. For more substantial injuries an tears, our stem cell protocol may be recommended.

Considering Ankle Surgery, Fusion or Replacement?

Osteoarthritis of the ankle usually occurs in ankles that have experienced trauma, infection, or injury. A smooth, slippery, fibrous connective tissue, called articular cartilage, acts as a protective cushion between bones. Arthritis develops as the cartilage begins to deteriorate or is lost. As the articular cartilage is lost, the joint space between the bones narrows. This is an early symptom of osteoarthritis of the ankle and is easily seen on X-rays.

As the disease progresses, the cartilage thins, becoming grooved and fragmented. The surrounding bones react by becoming thicker. They start to grow outward and form spurs. The synovium (a membrane that produces a thick fluid that helps nourish the cartilage and keep it slippery) becomes inflamed and thickened. It may produce extra fluid, which causes additional swelling.

As an alternative to surgery, fusion or replacement, Regenexx Procedures may help alleviate pain with a non-surgical injection procedure. Patients are often encouraged to walk the same day, and most experience little to no down time from the procedure.

Recent Regenexx Foot & Ankle Articles & Patient Stories

Lifelong Runner Gets Back on Track After Stem Cell Treatment

Scott had tried everything short of surgery to repair a running injury in his foot—physical therapy, chiropractic manipulation, special shoes, boot immobilization, acupuncture, massage therapy, Motrin, electrical stimulation, and so on. After struggling for years and...
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Flexor Hallucis Longus Tendon Pain: Is Surgery the Answer?

This is a story about Scott, a frustrated runner. One day in 2010 while out for a run, he suddenly heard a snap under his foot. He went from a normal, active life to trying years of different therapies without help. This is his story about how flexor hallucis longus...
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Gymnast Foot Problems: Could It Be Your Back?

At Regenexx, our focus is always treating the whole athlete. One of the unfortunate things that happens in our modern world of orthopedic hyper-specialists is that injured athletes are broken down into their parts that hurt. The knee guy sees someone with knee pain,...
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Plantar Fasciitis Release Surgery is a Bad Idea

Have you ever had Plantar Fasciitis? It’s one of those truly painful things that every inflight airline catalogue has 5 different gadgets to fix. Well it turns out that any one of those gadgets would be better than Plantar Fasciitis Release Surgery, according to...
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Ankle Ligaments Loose? You Need Ultrasound Stress Testing…

CF Ankle Ligament Ultrasound Stress Test Are your ankle ligaments loose? I used to have a bad ankle that I twisted running more than 20 years ago. Like many of my patients with ankle problems, mine wasn’t bad enough for surgery, but unlike many of my patients I...
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Changing Your Walk May Help Your Knee Arthritis

Can changing your walk help knee arthritis? The foot bone is connected to the knee bone, however, the modern 90 second orthopedic exam for a knee problem almost never includes an examination of the foot. Despite this oversight, a new study shows that how your foot...
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Dumb and Dumber: New PRP Ankle Sprain Research

  As you might be able to tell from reading these blogs, I love research. I read it voraciously, conduct studies, and publish it. But research, like all things can be smartly constructed or just plain dumb. I’d like to highlight a PRP ankle sprain study...
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Regenexx® Patient Success Stories

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    Orthopedics 2.0: How Regenerative Medicine Will Change Everything

    Surgery should always be a last option, but it's often presented to patients as the only option. Download Orthopedics 2.0 and educate yourself on how everything in your body works together in concert to maintain your physical wellbeing. When a single component in this chain is damaged, it can lead to a cascade of joint, spine and connective tissue problems, resulting in chronic pain. Using the Regenexx SANS approach, Orthopedics 2.0 walks you through a series of tests and exercises that you can do on your own to better understand where your own body is struggling to maintain proper stability and alignment, explaining the possible reasons and long term implications along the way. Orthopedics 2.0 is a FREE download from our site & it's an Amazon Top Seller!

    More Than 101,299 Downloads!

    Join Us For Our Next Webinar!

    Learn why Regenexx Procedures are superior to other orthopedic stem cell & platelet procedures available today.

    Join Dr. Chris Centeno, founder of the Regenexx Procedures, for this webinar explaining the procedures, as well as the ongoing research and innovation happening at Regenexx. The presentation will be followed by a Q&A session.

    Register for Webinar

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