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Regenexx® Offers the Broadest Array of Non-Surgical, Advanced Stem Cell & Platelet Procedures for Spine and Cervical Conditions.

Regenexx has a range of procedures developed to help patients avoid spine surgery and the side effects of epidural steroid injections. These procedures utilize the patient’s own natural growth factors or stem cells to treat bulging or herniated discs, degenerative conditions in the spine, and other back and neck conditions that cause pain.

The origin of spine pain is often misidentified. Our decade of experience in regenerative treatments for spine pain allows us to address as many factors as possible to gain insight into the true cause of the problem. We identify the most probable sources of pain and select the most appropriate treatment options available. Only then can the natural healing process be initiated using the safest, least invasive procedure possible.

Spine Patient Outcome Data & Commonly Treated Spine / Cervical Conditions

Regenexx is the only stem cell treatment network to publish this type of analysis of patient stem cell procedure outcome data. The analysis is made possible thanks to the massive numbers that are compiled throughout the years in the Regenexx patient registry, which tracks patient outcomes at regular intervals following all of the stem cell procedures we offer.

Note: This patient outcome data is not part of a controlled trial. Every patient becomes part of a registry to track outcomes and any complications. This data is a compilation of patient input to the Regenexx Patient Registry at regular intervals following their Regenexx Procedure. In addition, none of this data may be reproduced in any way or displayed elsewhere without prior written permission from Regenerative Sciences.

  • PL-Disc Outcome Data

    This outcome information summarizes the patient registry data for Regenexx Platelet Lysate Spine Procedures using Platelet Lysate (created from a patient’s own blood).

    View PL-Disc Outcome Data
  • PL-Disc vs. Steroid Epidural Outcome Data

    This data compares two groups of patients who received epidural steroids vs. PL-Disc and looks at their results at 3 month and 6 month intervals using a Functional Rating Index (FRI), which measures things like pain as well as the ability to walk, sit, lift, bend, etc.

    View PL-Disc vs. Steroid Epidural Outcome Data
  • Stem Cell Procedure Safety

    Regenexx has published more data on stem cell safety in peer reviewed medical research for orthopedic applications than any other group world-wide. This is a report of 1,591 patients and 1,949 procedures treated with the Regenexx Stem Cell Procedure. Based on our analysis of this treatment registry data, the Regenexx Stem Cell Procedure is about as safe as any typical injection procedure, which is consistent with what we see every day in the clinic.

    View Stem Cell Procedure Safety

Commonly Treated Spine & Cervical Conditions

This is not a complete list, so please contact us or complete the Regenexx Candidate Form if you have questions about whether you or your condition can be treated with these non-surgical procedures.

  • Annular Tear
  • Arthritis of the Spine
  • Back Pain
  • Bone Spurs
  • Bulging Disc
  • Canal Stenosis
  • Collapsed Disc
  • Degenerative Disc Disease
  • Degenerative Spine
  • Disc Extrusion / Protrusion
  • Facet Joint Syndrome
  • Failed Back Surgery Syndrome
  • Foraminal Stenosis
  • Herniated Disc
  • Herniated Nucleus Pulposus (HNP)
  • Neck Pain
  • Nerve Pain
  • Pinched Nerves
  • Radiculitis
  • Radiating Nerve Pain
  • Ruptured Disc
  • Sciatica
  • SI Joint Syndrome
  • Slipped Disc
  • Spinal Stenosis
  • Spondylosis
  • Torn Disc
  • Radiculopathy

How it Works

Stem Cell Treatments

Same Day Stem Cell Protocol (USA & International) & Cultured Stem Cell Procedure (Cayman Islands Only)

Adult stem cells are cells from your own body that can renew themselves and turn into other cells (differentiate). They live inside all of us in various tissues, poised to leap into action to repair damage as it occurs. As we age or have big injuries, we may not be able to recruit enough of these cells to the site to fully repair the area. Regenexx Stem Cell Procedures help overcome this problem by extracting stem cells from an area of high volume, then concentrating the cells and reinjecting them into the damaged area to help the body heal naturally.

Our Patented Stem Cell Procedures can be used for a wide range of conditions and are the tool of choice for injuries, arthritis and other conditions that may be more significant than what may be treated with our Platelet Rich Plasma or Platelet Lysate Procedures.

Blood Platelet Treatments

Super Concentrated Platelet Rich Plasma & Advanced Platelet Lysate Procedures (USA & International)

Platelet Rich Plasma (PRP) and Platelet Lysate Injection Treatments contain healing growth components from your own blood that increase your body’s natural ability to repair itself. The use of PRP to repair joint, tendon, ligament, and muscle injuries is becoming well known, thanks to exposure from professional athletes. Platelet injection treatments are effective because they have a stimulating effect on the stem cells within the targeted area, making those stem cells work harder to heal damaged tissues.

Our Advanced Platelet Procedures are more pure and concentrated than those created by the automated machines used at most regenerative medicine clinics. Platelet procedures are commonly used for soft tissue injuries, mild arthritis and spine conditions.

Why Regenexx is a Better Option than Fusion Surgery or Steroid Epidural Injections:

Fusion surgery is a highly invasive procedure and is more likely to cause complications (complications occur in 36% of fusion patients). 76% still required narcotics for pain and missed 3 times as much work as those who didn’t have surgery.

A steroid epidural is an injection that places steroid medication around irritated or inflamed nerves in the spine. While they do help patients avoid surgery, epidurals use very high dose steroids that can cause severe side effects and actually reduce the body’s ability to heal.

Regenexx offers a variety of minimally invasive procedures that deliver ultra-precise spinal injections of platelet lysates or stem cells where needed utilizing advanced imaging guidance.

The Spine Owner’s Manual — How to Avoid Back Pain & Life Altering Surgery

The Spine Owner’s Manual Download

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Written by Dr. Chris Centeno, this e-book delves into the spine and how it functions within the human musculoskeletal system and the body as a whole. Everything within the body works together, like a precisely tuned symphony, to support our well-being, and a healthy spine and all of its component parts (e.g., spinal nerves, ligaments, muscles, etc.) are critical to full-body health. When a single component in the spinal chain is damaged, it can lead to a cascade of problems not only in the musculoskeletal system but throughout the body and even further spinal damage when it goes untreated. The result is chronic pain anywhere in the body that with the proper diagnostic approach can be traced back to the damage in the spine.


Platelet Treatments for Pain from Bulging or Herniated Discs

Bulging or Herniated Disc Treatment

Bulging & Herniated Discs Explained

A bulging disc is also called a disc protrusion or bulge. This means that the outer covering of the disc (annulus) is partially torn or damaged and the inner gel is causing the area to bulge. This can put pressure on a spinal nerve and cause numbness and tingling (sciatica).

A herniated disc is also called a disc extrusion, slipped disc, sequestration, or “HNP” (Herniated Nucleus Pulposis). This means that the outer covering of the disc (annulus) is completely torn or damaged and the inner gel squirts out. This can put pressure on a spinal nerve or cause severe swelling and lead to numbness and tingling (sciatica).

Treating Bulging and Herniated Discs

Regenexx Platelet Lysate can offer relief from lower back or neck pain, buttock and leg pain, or numbness and tingling in the arms, hands, legs or feet. It’s a safe, non-surgical treatment alternative for patients suffering from bulging discs and herniated cervical, thoracic, or lumbar disc related problems.

Most patients with bulging or herniated discs respond well to a platelet lysate injection into the space surrounding the inflamed spinal nerves. Other clinics resort to an injection of stems cells directly into a patient’s disc. While this can sometimes ultimately be necessary, our platelet lysate procedure is less invasive and lower risk. Nobody other than Regenexx offers this type of procedure, which utilizes natural growth factors produced from the patient’s own blood platelets. Regenexx is the only provider with experience in both stem cells and platelet lysate so we are uniquely able to determine the best treatment options to address your source of pain.

Better than Steroid Epidurals

A steroid epidural is an injection that places steroid medication around irritated or inflamed nerves in the spine. While they do help patients avoid surgery, epidurals use very high dose steroids which can reduce the body’s ability to heal and can lead to severe side effects.

Regenexx Platelet Lysate is a minimally invasive alternative to a steroid epidural injection that offers a very limited recovery period. It uses natural growth factors from the patient’s own body, derived from blood platelets, helping patients avoid surgery and the negative side effects of steroids.

Stem Cell & Platelet Treatment for Degenerated Disc Pain

Advanced Treatments for Degenerative Discs

Degenerated disc patients tend to lose disc height which can lead to a wide range of complications.

  • Compressed nerves (stenosis)
  • Facet joint overload leading to arthritis
  • Lax ligaments that result in overall spinal instability

Our treatment protocol focuses on platelet and/or stem cell technologies deployed to treat sloppy disc movement due to lax ligaments and arthritic facet joints.

Each of these critical areas above may benefit from different types of procedures.

Only Regenexx has the experience and the broad spectrum of procedures that allow for effective treatment of all of these conditions. Regenexx procedures provide non-surgical treatment options for patients suffering from the complications associated with degenerative disc disease. By carefully targeting the right procedure to the impacted areas of the spine, patients can avoid spinal fusion surgery or frequent high dose steroid epidural injections and their associated side effects.

Degenerative Disc Procedure Infographic

Stem Cell Treatment for Torn & Painful Discs

Bulging or Herniated Disc Treatment

Torn and Painful Discs Explained

Disc tears are also called annular tears or HIZs (High Intensity Zones) on MRI
images. A patient with a painful and torn disc has “disogenic pain”. The outer
covering of the disc can be torn due to injury and painful nerves can grow into
the area, leading to low back pain, usually with sitting or activity. In addition,
the tear in the disc may lead to noxious chemicals escaping and irritating the
spinal nerve, which can lead to sciatica.

Patients with this type of disc damage and pain generally have the best response from a Regenexx Stem Cell injection procedure.

This non-surgical procedure uses stem cells isolated from the patient’s own bone marrow. The marrow is collected using a special needle during a simple office procedure. The harvesting procedure is well tolerated by patients and many patients report experiencing no pain. After collection, the marrow is centrifuged to concentrate and purify the stem cells while removing unneeded cells. These stem cells, along with a preparation of concentrated blood platelets, are injected into the damaged disc using advanced imaging guidance.

Why our spine stem cell treatments are better than others

The typical stem cell procedure provider uses an automated one-size-fits-all centrifuge to prepare cells. At Regenexx, our processing allows us to custom tailor our regenerative mixtures for your condition and our patented two-tier processing results in 10 to 20 times more stem cells available for your treatment. While some practices add platelet rich plasma to their stem cell concentrate, we use a proprietary super concentrated platelet mix. By mixing our second generation, lab prepared Platelet Rich Plasma (which contains slow release growth factors) and our third generation platelet lysate (immediately available growth factors), we were able to get adult stem cells to grow many times more than just PRP or platelet lysate alone.

The Most Advanced Orthopedic Stem Cell Protocol in the World

  • 100% Focused on Orthopedic Conditions & Producing the Best Possible Outcomes
  • Up to 20 Times More Stem Cells Than Standard Stem Cell Procedures
  • The Most Researched Stem Cell Protocol for Orthopedic Conditions
  • Image-Guided Cell Injections & Harvesting for Absolute Precision
  • Bone Marrow Derived Stem Cells Outperform Fat Derived Cells
  • A Complete Stem Cell Protocol - Not a Single Procedure
  • Annually Published Patient Outcomes and Safety Data

Explore The Regenexx Difference

Regenexx Procedures at a Glance

Typical Condition Severity

$$$ Cultured Stem Cell Procedure (Cayman Islands Only)*
$$ Stem Cell Treatment Protocol (USA & Worldwide)
$ Platelet Rich Plasma & Platelet Lysate
Strains, muscle, ligament & tendon tears, overuse injuries, tendonitis & tendonosis, minor arthritis, joint maintenance, bulging or herniated discs, degenerative discs.
More severe muscle, ligament & tendon tears (including complete tears), joint arthritis, degenerative joint conditions, torn spinal discs, degenerative discs, avascular necrosis, bone conditions & non-union fractures.
Similar to USA Stem Cell Treatment, but stem cells are cultured to greater numbers.* Recommended for severe injuries, arthritis, advanced degenerative conditions, more severe spine conditions.
*Advanced culture expanded stem cell procedure-not approved by the USFDA and available only through licensed sites where culturing cells are the practice of medicine.

Recent Regenexx Spine Articles & Patient Stories

Spondylolysis Recovery Time: Avoiding the Knife

Spondylolysis is common in disturbingly young athletes who are born with weakened or disconnected areas of their spine. Sometimes this break in the spine bone heals, and sometimes it doesn’t. When the spot doesn’t mend, the patient usually undergoes a big...
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LASER Spine Surgery Side Effects: Meet the Thoracodorsal Fascia

Thoracodorsal Fascia Injury Causing Low Back Pain Have you seen those new compression garments athletes wear to try to improve performance? The idea is that by adding compression to the muscles, the ultratight shirts and pants will make the muscles contract better....
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New Research: An MRI with Stenosis Doesn’t Diagnose Your Pain

  We have all been taught that what shows up on an MRI is incredibly important—so much so that countless invasive surgeries are launched based on a picture and a cursory exam. Despite this, study after study continues to show just how bad MRI is at predicting...
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What Percentage is “Useless Orthopedic Surgery” Based on Research?

This is a post that some orthopedic surgeons will hate but that needs to be written. This week, I decided to try and estimate the number of orthopedic surgeries that were still being done despite research showing they didn’t work. When I was done, I realized...
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We Publish a Low Back Stem Cell Research Paper

Despite being the first clinic in the world to inject stem cells into low back discs, we’ve had a piece missing in our research portfolio. We’ve published on knees, hips, shoulders, and other joints, and while we’ve included low back disc cases in...
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Listening to the Body on Exam: An Old Car Crash Upper Back Injury Speaks…

One of the most famous physicians of all time is Sir William Osler, the father of the modern residency program that uses real-world clinical experiences to train young doctors. One of his most famous sayings was, “Listen to your patient; he is telling you the...
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Stem Cell Disc Injection: The Hammer and the Nail

There’s a saying in medicine, “When all you have is a hammer, everything looks like a nail”. Meaning that if all the doctor knows how to do for a given problem is one treatment, then he or she tends to use that treatment when it’s not...
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Regenexx® Patient Success Stories

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    Join Us For Our Next Webinar!

    Learn why Regenexx Procedures are superior to other orthopedic stem cell & platelet procedures available today.

    Join Dr. Chris Centeno, founder of the Regenexx Procedures, for this webinar explaining the procedures, as well as the ongoing research and innovation happening at Regenexx. The presentation will be followed by a Q&A session.

    Register for Webinar

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