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The Regenexx® Patented Stem Cell Procedure for Non-Union Fractures is a next generation, non-surgical stem cell treatment for people suffering from non-healing fractures.

The procedure works without surgery by greatly increasing the concentration of a person’s own stem cells in the non-healing fracture area, which boosts the bone’s own ability to heal itself naturally.

Non-Union Fracture Treatment
5 Weeks Post Stem Cell Injection

Traditional options for the treatment of non-union fractures typically involves surgery, which can be painful and require months of rehab, with no guarantees of success. As an alternative to surgery, Regenexx® stem cell procedure patients typically experience little to no down time from the procedure.

Treating Non-Union Fractures with Stem Cells

Most bone fractures heal without difficulty. However, fractures that demonstrate motion of the bony ends with incomplete healing more than 6 months after injury are called non-union fractures.

Of the estimated 6 million bone fractures in the United States each year, approximately 300,000 will develop slow (delayed union) or incomplete healing (non-union). The reasons for a non-union (or failed) fracture may include:

  • Complicated, multisegmental factures (severe comminution)
  • Open fractures
  • Fractures associated with tumors (pathologic fractures)
  • Infection
  • Insufficient fracture immobilization (fixation)
  • Inadequate blood supply
  • Poor nutrition
  • Chronic disease states (diabetes, renal failure, metabolic bone disease)
Regenexx - Safer Than Surgery
  • Stem Cell Procedure Safety

    Regenexx has published more data on stem cell safety in peer reviewed medical research for orthopedic applications than any other group world-wide. This is a report of 1,591 patients and 1,949 procedures treated with the Regenexx Stem Cell Procedure. Based on our analysis of this treatment registry data, the Regenexx Stem Cell Procedure is about as safe as any typical injection procedure, which is consistent with what we see every day in the clinic.

    View Stem Cell Procedure Safety
Non-Union Fractures Research
Click to Review This Study by Regenexx Doctors

Regenexx Published Research on Treating Non-Union Fractures

While published research on treating non-union fractures with stem cells has been limited, Regenexx doctors published a paper on it back in 2008. The research included patient case studies and conclusions. However, unlike more common orthopedic conditions, such as arthritis, the small pool of potential patients for this treatment was quite small. Since that time, our findings continue to show stem cells to be a promising treatment for those with issues relating to bone healing.

Another study supporting enhanced fracture healing through stem cell injections

A story from our blog in 2015, showing bone healing from stem cell injections

The Best Possible Patient Outcomes

At Regenexx® no corners are cut. Our regenerative procedures are 100% focused on producing the best possible patient outcomes, without trying to balance quality with profitability. Continue to learn why we’re the #1 orthopedic stem cell procedure

A Complete Stem Cell Protocol – Not Just a Single Procedure

The Regenexx Patented Stem Cell Protocol has been researched and continually improved for more than a decade. The protocol used in the United States typically involves a series of injections that take place over the course of approximately one week. The Stem Cell extraction and reinjection happens during the same day, while the other two injection steps happen before and after the same day stem cell procedure and are designed to enhance the results of the stem cell procedure.

100% Focused on Orthopedics

We don’t treat everything and we’re proud of that fact. We are orthopedic specialists. Each doctor in the Regenexx Network is a musculoskeletal expert trained in our procedures and have proven skills in advanced injections for the body areas that they are certified to treat.

Up to 20 Times More Stem Cells Available for Your Treatment Using Patented Cell Processing Procedure

At Regenexx®, we’re continually improving our processes to maximize the available stem cells for your treatment. Our patented multi-tier lab technique typically yields 10 to 20 times more stem cells than is possible using the simple automated equipment utilized by most stem cell clinics.

Image-Guided Injections and Harvesting

Even experienced orthopedic specialists cannot hit an exact spot without taking a look inside. The imaging technology that we use during your procedure allows us to not only see the anatomy of the area being injected, but we have live visualization of the needle and the distribution of the injected cells. Precise needle placement for stem cell harvesting and reinjection is a key element in producing the best possible outcomes.

Backed by the Most Research

Regenexx® is the original orthopedic stem cell treatment in the United States and we’re responsible for a very large portion of the published orthopedic stem cell literature available today.
Published Research Articles

Bone Marrow Derived Stem Cells

Research has shown that stem cells derived from bone marrow (rather than fat) are most effective for treating orthopedic injuries and conditions. We utilize advanced imaging guidance during the stem cell harvesting procedure to ensure the cells are being obtained from the exact area in the hip that is known to be rich in mesenchymal stem cells.

Published Patient Outcome Data & Transparency

At Regenexx® we publish our patient outcome data on a regular basis and make it available to the public on our website and in peer-reviewed research papers. Regenexx patients are tracked in a registry for functional improvements, pain scales, outcomes and safety data.
Patient Outcome Data

Non-Union Fracture Patient Testimonials

“The results were absolutely amazing. Just 24 hours later, I had no pain at all in my pelvis. In four weeks, a CAT scan showed the beginnings of the healing process, and in eight weeks another scan showed a moderate union of the fractures. I’m now living in Boulder, walking on my own, without a walker, and I have no pain whatsoever. This technique, which is minimally invasive, is a complete miracle as far as I’m concerned. I want the whole world – especially seniors – to know that injuries such as femoral, hip and pelvic fractures don’t have to diminish your quality of life. You can be healthy and moving forward again with this procedure.” – Read the full story

“Regenexx did what nothing else could. Given the minimal invasiveness of the procedure and the outstanding results, I would highly recommend it for anyone.” – Read the full story

Are You Suffering from a Non-Union Fracture?

If you are suffering from a fracture that is not healing properly, you may be a candidate for this procedure. Please complete our Regenexx Procedure Candidate Form below or call us at 888-525-3005.

Regenexx Candidate Form


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