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The Interventional Orthobiologics Blog

Kratom and Interventional Orthobiologics Procedures

As you know, I often write about what I experience seeing patients. While Kratom has been on the periphery of my consciousness like it probably has been for many physicians, this past week, it was thrust to the forefront. This “drug” sold in gas stations and online turns out to be a potent opioid receptor…read more

2023 PRP RCT Infographic and Study Failure Analysis

Almost every year, I try to spend significant time diving into the literature on interventional orthobiologics and summarizing it. This helps me understand where we are in the evolution of the literature and hopefully provides some insight into what’s working and what’s not. This year I summarized the entire published literature on PRP injections for…read more

Disc Injections With Platelet Raisins and Protein Syrup

The last blog I published was on the mounting evidence for using PRP to treat the common causes of spinal pain. However, in that literature review, one study stood out. That research was abruptly halted at eight weeks, which was curious. As I sat down to read and analyze this paper in more detail, it…read more

Is There Solid Research on Using PRP to Treat Spinal Pain?

Art: Credit Dall-E with the prompt: “A human spine in 3D surrounded by red blood cells in the style of impressionism.” As you know, I often write about what I experience. This week an interventional spine physician questioned whether PRP would be useful in the treatment of lumbar radiculopathy or painful facet joints in the…read more

Filling a Tissue Defect With Wharton’s Jelly Is Not Homologous Use: The Regenative Labs Warning Letter

I’ve blogged on Regenative Labs quite a bit. In part, that’s because this has been an interesting player in the regenerative medicine space. They first cooked up a plan to “fill tissue defects” and claimed that you could bill Medicare for their Wharton’s Jelly products when used to treat knee arthritis. When CMS pushed back,…read more

Why the Idea That an ACL Can Heal Itself Is Surgical Sacrilege

As I have written before, if modern surgical sports medicine has one sacred cow, it’s ACL reconstruction. That’s why the fact that we have dozens of MRI examples of non-healing torn ACLs improving with our Perc-ACLR procedure has raised eyebrows. Now a new study that shows that some ACLs can heal themselves has apparently angered…read more

What the Regenerative Medicine Industry Can Learn from the Failed Titanic Sub

As I begin this blog, I’m saddened by the news of the implosion of the Titanic Sub. Like many, I thought there could be some miraculous rescue of these poor souls. My heart goes out to the families of these five people. In medicine, tragedies like this are always used as a learning experience to…read more

Can You Use ChatGPT to Do Medical Research?

If you read this blog regularly, you know that I’m a big fan of AI and predict that it will change science and medicine for the better. However, as ChatCPT came into focus this past few months, several colleagues have claimed that you can now use it to do online medical research and generate text…read more
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