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My Brother’s Messed Up Patellar Tendon and Stem Cells

POSTED ON IN Uncategorized BY Chris Centeno

patellar tendon healing without surgery

My brother has been a lifelong runner. So when he ruptured his patellar tendon playing tennis and then had it surgically repaired, the big question was whether he could return to running. The answer? Not until some stem cell help. Let me explain.

The Patellar Tendon

The patellar tendon attaches the bottom of the knee cap to the leg bone (tibia). It’s more commonly degenerative and beat up, but in rare instances, it can completely rupture. When that happens, the knee cap ends up in the lower thigh, and the only option is a surgical repair.

My Brother’s Injury

My brother was a high school and then college cross-country runner for the Naval Academy (he’s the guy in the “Creek” jersey above) and then became an avid jogger once he finished the academy. One day he was playing tennis and then cut suddenly and ruptured his patellar tendon. Given the massive tear and retraction of the patella, there was no other option but surgery. However, his running was never really the same after that. In fact, it was painful to watch him hobble. After several years of hobbling around and pushing through pain, he finally got to the point where he couldn’t run, which is about when I entered the picture.

The problem for my brother was that like most surgical repairs, his was far from perfect and never fully healed in a way that matched his natural tendon. Meaning on MRI and with a more detailed ultrasound exam, the tendon was a disorganized mess. What do I mean?

Tendon 101


tendon structure

In order for tendons to work properly, they need to be organized like strands of a rope. The image to the left shows that collagen fibrils (the threads of the rope) join together to make a fiber bundle (the strand of the rope) and that many bundles make a tendon. As you can see, it’s very well organized. My brother’s tendon had these strands of the rope going every which way, and it was hypertrophied. That last point is key.

Hypertrophy in the world of tendons is likely the most common thing we see that indicates a weak tendon. This means that the body is trying to repair the site by throwing more tissue at the problem, so it makes the tendon bigger. The goal is to get the overall tendon to be stronger so it won’t fail, but the body isn’t able to produce normal dense tendon. Hence, the tendon gets bigger and bigger.

My Brother’s Procedure and Result

My brother had a Regenexx-SD one-day stem cell procedure in April of 2018. I carefully fenestrated this scarred down and disorganized tendon and injected his own bone marrow stem cells. He was in significant pain for a few days, and then things got slowly better as they so often do with tendons. Meaning, full tendon or ligament healing can take a good six to nine months or longer. I knew he was doing better and running more, but I didn’t have a good sense of where he was until he sent me this picture and text yesterday:

“Hi Chris,
Out in HNL… I just ran up diamond head pain free for the first time in years… about a 6 mile trek… thank you for making it possible!”

knee tendon healing

The upshot? I’m glad I was able to help this messed up patellar tendon and my big brother! There really wasn’t a surgical option here as that would have created more mess. This is one area where only a high-dose injection of his own bone marrow stem cells would do the trick!

    *DISCLAIMER: Like all medical procedures, Regenexx® Procedures have a success and failure rate. Patient reviews and testimonials on this site should not be interpreted as a statement on the effectiveness of our treatments for anyone else.
    Providers listed on the Regenexx website are for informational purposes only and are not a recommendation from Regenexx for a specific provider or a guarantee of the outcome of any treatment you receive.


    Bob Garrasi says

    Dr. Centeno,

    About 22 months ago i jumped off my back porch and ruptured both quad tendons. had surgery the same day. rehab inpatient for 6 weeks, where the phys therapist had me do an excercise that appears to have screwed up my left quad tendon.

    I've also had one of your procedures done on my right shoulder (torn rotator cuff) in Burlington, VT. Outstanding results!

    So having read the above article, I'm wondering whether the ruptured quad tendons could benefit from the same procedure that your brother had done. Please advise further. Thanx.


    Regenexx Team says

    Hi Bob,
    They may. We'd need more information through a Candidacy review, or exam. Do you have any recent MRI imaging?


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    About the Author

    Chris Centeno

    Christopher J. Centeno, M.D. is an international expert and specialist in regenerative medicine and the clinical use of mesenchymal stem cells in orthopedics. He is board certified in physical medicine as well as rehabilitation and in pain management through The American Board of Physical Medicine and Rehabilitation.…

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