How Stem Cells Work: Contact Inhibition or How to Stop Making Copies of Yourself

POSTED ON 2/4/2014 IN Regenerative Medicine Education BY Christopher Centeno

How Stem Cells Work - Part 6

Today's installment of How Stem Cells Work sounds daunting, but is pretty simple. What is the big difference between the safety profile of adult stem cells (like the mesenchymal stem cells (MSCs) we use), embryonic stem cells, and the newer induced pluripotent stem cells (iPS)? The single topic that jumps out is contact inhibition. MSCs are naturally programmed to stop growing when they touch each other. Not so with other stem cells types, hence the concern for embryonic stem cells and iPS cells and tumors. Watch my 1 min video explanation above!

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